ABSTRACT
Chondrosarcoma is a malignant tumor of cartilaginous origin. The most common type in the jaw is mesenchymal. Chondrosarcoma in maxillofacial region is an uncommon tumor and maxilla is more commonly affected than mandible. The aim of this paper is cases report of a rare chondrosarcoma of the mandible. A 65-year-old woman was referred to Oral Medicine Department of Mashhad dental school with swelling over the buccal and lingual aspect of the anterior mandible. Swelling had been present for 1 year and had increased gradually in six over time. The patient did not have any systemic disase and was not currently taking any medications. Extraoral examination did not reveal any obvious facial swelling, asymmetry or cervical lymphadenopathy. Intraoral examination revealed an exophitic nodular and tendered lesion with smooth and purple surface. IT was firm to rubbery in buccal aspect and bony in lingual surface with 3x3.5 diameters. Occlusal and panoramic radiographs revealed the multibular well defined and mixed radiolucent-redioopague lesion from right mandibular first premolar to left mandibular first premolar. Subperiosteal ossification is revealed in the occlusal cross sectional radiography. Histopathological examination revealed chondrosarcoma [grade I]. The patient was advised to undergo surgery, and the tumor was respected by segmental mandibulectomy. Clinical and radiographic feature at chondrosarcoma are varied, the incidence of this lesion in unusual location like anterior of jaw with a well-defined feature and ossification could lead to clinician error and delaying treatment. Considering age, course and invasion could be helpful in diagnosis